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Tag: Advanced

Understanding Kidney Stones: Advanced Diagnosis, Treatment Options, and Prevention Strategies

Dr Akila V Nephrologist, Aster CMI Hospital, Bangalore

Kidney stones, also known as renal calculi, are hard deposits formed from minerals and salts that crystallize in the kidneys. Affecting millions worldwide, these stones can cause severe pain and discomfort.

The Formation of Kidney Stones
Kidney stones form when urine becomes concentrated, allowing minerals to crystallize and stick together. Several types of stones exist, including calcium oxalate, calcium phosphate, struvite, uric acid, and cystine stones. Factors contributing to stone formation include dehydration, dietary choices, obesity, and certain medical conditions.

Advanced Diagnosis Methods.
Accurate diagnosis of kidney stones is crucial for effective treatment. Here are some advanced diagnostic methods used by healthcare professionals:

1. Imaging Tests
Ultrasound is a non-invasive technique that employs sound waves to generate images of the kidneys and urinary tract, enabling healthcare professionals to visualize stones without the risk of radiation exposure. This method is especially beneficial for pregnant patients and individuals requiring frequent assessments. A computed tomography (CT) scan is an advanced imaging modality that delivers highly detailed cross-sectional images of the kidneys. It is capable of rapidly identifying even small stones and evaluating their precise location, size, and any possible blockages within the urinary tract. Traditional X-rays can detect larger stones; however, they are less effective for certain types, such as uric acid stones, which may not be visible through this imaging method.

2. Laboratory Tests
Laboratory evaluations play a crucial role in diagnosing conditions related to kidney stones. A 24-hour urine collection is conducted to analyze the concentrations of substances that contribute to stone formation, such as calcium, oxalate, and uric acid. This assessment is instrumental in pinpointing individual risk factors. Additionally, blood tests can provide insights into elevated levels of calcium or uric acid, which may suggest an increased likelihood of developing stones, while also aiding in the evaluation of kidney function.

Treatment and Surgery

1. Medications:
Medications are commonly utilized to alleviate pain, with analgesics prescribed to ease discomfort. Additionally, alpha-blockers may be administered to relax the ureteral muscles, promoting the passage of stones.

2. Non-invasive techniques:
Non-invasive techniques, such as Extracorporeal Shock Wave Lithotripsy (ESWL), employ sound waves to fragment stones into smaller pieces that can be expelled through urine. For cases requiring a more hands-on approach.

3. Minimally Invasive Surgery:
Minimally invasive surgical options like ureteroscopy involve the insertion of a slender tube equipped with a camera to either remove or disintegrate the stone. In instances of larger stones, Percutaneous Nephrolithotomy (PCNL) may be performed, which entails a small incision in the back to directly extract stones from the kidney.

4. Open Surgery:
Open surgery might be warranted for particularly large or complex stones, although this method is more invasive and typically involves a lengthier recovery period.

Preventive Measures:

1. Hydration:
Drinking adequate water is essential to dilute urine and minimize the concentration of stone- forming minerals. Aim for at least 8-10 glasses of water daily.

2. Dietary Changes:
Decrease Sodium Consumption: Cutting back on salt can lead to a reduction in the amount of calcium excreted in urine, thereby lowering the likelihood of developing calcium stones.

Restrict Oxalate-Heavy Foods: Consuming foods that are rich in oxalates, including spinach, nuts, and chocolate, can increase the risk of stone formation, particularly for individuals susceptible to calcium oxalate stones.

Calcium Consumption: Although it may appear paradoxical, acquiring calcium through food sources instead of supplements can effectively reduce the risk of stone formation.

3. Maintain a Healthy Weight: Obesity is linked to a higher risk of kidney stones. A balanced diet and regular exercise can help manage weight effectively.

4. Monitor Medical Conditions: Managing underlying health issues like diabetes, hyperparathyroidism, or inflammatory bowel disease can significantly reduce the risk of kidney stone formation.

Audit Insights: Harnessing Advanced Technologies While Avoiding Over-Reliance Risks

Mumbai, October 24, 2024: Chartered Accountants Australia and New Zealand (CA ANZ) and ACCA (the Association of Chartered Certified Accountants) have released the Audit and technology playbook: A practitioner’s guide, a comprehensive guide aimed at helping audit professionals adapt to the rapidly advancing technological landscape.

The development of advanced technologies such as artificial intelligence (AI), machine learning and blockchain is reshaping the audit profession. For example, Generative AI alongside increasingly sophisticated data analytics allows auditors to analyse huge amounts of data in just a few seconds, uncovering patterns that were previously invisible and providing greater confidence than traditional methods.

The playbook provides actionable strategies to equip auditors with the skills and tools necessary to navigate this digital transformation. It addresses the opportunities and risks it presents, identifies key trends and provides a framework for audit practices – particularly small and medium-sized practitioners (SMPs) – to adapt.

It also emphasises the importance of balancing technological advances with professional ethics, judgement and human oversight, and highlights the risks of over-reliance on technology.

Simon Grant, CA ANZ Group Executive – Advocacy and International, emphasised the importance of embracing new technologies while maintaining the core principles of the profession. He said: ‘Technology is opening up new possibilities in auditing that were out of reach only a decade ago. However, the human element remains as important as ever. Our professional scepticism, judgment, and ethics must remain at the forefront as we integrate these new tools into our practices.’

Mike Suffield, Director of Policy and Insights at ACCA, said: ‘Advanced technologies can allow auditors to gain deeper insights into the businesses they audit. But there’s a very real danger of relying too heavily on technology, such as through automation bias where technology subtly influences an auditor’s judgment.’

Key sections of the playbook include guidance on developing a digital strategy, investing in staff skill development, and implementing governance structures to maintain audit integrity.

The guide was informed by extensive research and roundtable discussions with members across several markets.